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Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
JoVE Journal
Medicina
Author Produced
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JoVE Journal Medicina
Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
DOI:

15:49 min

October 16, 2013

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Capitoli

  • 00:00Titolo
  • 00:59Content
  • 01:54Setting up the Endoscopy System
  • 03:12Anesthetizing the Mouse
  • 04:05Endoscopy
  • 08:02Biopsy
  • 09:12Recovery
  • 09:25Scoring for Colonic Inflammation

Summary

Traduzione automatica

Over the past few years, new generation endoscopes have emerged as important diagnostic research aids for evaluating murine colitis and colorectal tumors. We present herein a detailed protocol for endoscopic assessment of inflammation and colorectal tumors in mice, as well as a novel scoring system that uses decimal identifiers to document the endoscopic severity of colitis and colorectal tumors.

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