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Marble Burying and Nestlet Shredding as Tests of Repetitive, Compulsive-like Behaviors in Mice
JoVE Journal
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JoVE Journal Comportamento
Marble Burying and Nestlet Shredding as Tests of Repetitive, Compulsive-like Behaviors in Mice
DOI:

06:50 min

December 24, 2013

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Capitoli

  • 00:05Titolo
  • 01:22Animal Handling
  • 01:48Marble Burying Test
  • 03:26Nestlet Shredding Test
  • 04:47Results: Compulsive-like Behaviors in Mice
  • 06:10Conclusion

Summary

Traduzione automatica

Disease, head injury, genetic modifications, and treatment of mice with drugs can have profound effects on behavior. Utilizing well-characterized and validated approaches such as marble burying and nestlet shredding, compulsive-like behaviors can be documented accurately in mice as models of human obsessive-compulsive disorder and autism spectrum disorder.

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