An Alkali-burn Injury Model of Corneal Neovascularization in the Mouse

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JoVE Journal Medicina

An Alkali-burn Injury Model of Corneal Neovascularization in the Mouse

DOI:

10.3791/51159-v

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10:52 min

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April 07, 2014

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Chastain Anderson*¹, Qinbo Zhou*¹, Shusheng Wang²

¹Department of Cell and Molecular Biology,Tulane University, ²Department of Ophthalmology,Tulane University

Capitoli

00:05Titolo
01:27Alkali-burn Injury and Compound Treatment
03:35Clinical Assessment
05:42Corneal Staining and Flat Mounts
08:38Results: Corneal Neovascularization Post Alkali-burn Injury
10:32Conclusion

Summary

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Neovascularization (NV) of the cornea can complicate multiple visual pathologies. Utilizing a controlled, alkali-burn injury model, a quantifiable level of corneal NV can be produced for mechanistic study of corneal NV and evaluation of potential therapies for neovascular disorders.

An Alkali-burn Injury Model of Corneal Neovascularization in the Mouse

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