Rivista
/
Neuroscienze
/
In vivo Imaging of Optic Nerve Fiber Integrity by Contrast-Enhanced MRI in Mice
JoVE Journal
Neuroscienze
È necessario avere un abbonamento a JoVE per visualizzare questo.  Accedi o inizia la tua prova gratuita.
JoVE Journal Neuroscienze
In vivo Imaging of Optic Nerve Fiber Integrity by Contrast-Enhanced MRI in Mice

In vivo Imaging of Optic Nerve Fiber Integrity by Contrast-Enhanced MRI in Mice

DOI:
10.3791/51274-v

•

11:38 min

•

July 22, 2014

•

, , , , , , ,
1Hans Berger Department of Neurology,Jena University Hospital, 2Immunology, Leibniz Institute for Age Research,Fritz Lipmann Institute, Jena, 3Institute of Diagnostic and Interventional Radiology, Medical Physics Group,Jena University Hospital

Capitoli

  • 00:05Titolo
  • 02:41Intravitreal Manganese Injection
  • 04:32Preparing Animals for the MRI
  • 07:25MRI Data Analysis
  • 08:45Results: Contrast-enhanced MR Imaging
  • 10:33Conclusion

Summary

Traduzione automatica

Traduzione automatica

This video illustrates a method, using a clinical 3 T scanner, for contrast-enhanced MR imaging of the naïve mouse visual projection and for repetitive and longitudinal in vivo studies of optic nerve degeneration associated with acute optic nerve crush injury and chronic optic nerve degeneration in knock-out mice (p50KO).

Tags

In Vivo ImagingOptic NerveMRIContrast EnhancementMEMRIRodent Visual SystemRetinal Ganglion CellsAxonal DegenerationAxonal RegenerationSynaptic PlasticityMnCl2NF-κB P50KO Mice

Article

Embed

AGGIUNGI ALLA PLAYLIST

Usage Statistics

Video correlati

Methods for Experimental Manipulations after Optic Nerve Transection in the Mammalian CNS

Transfection of Mouse Retinal Ganglion Cells by in vivo Electroporation

Functional Neuroimaging Using Ultrasonic Blood-brain Barrier Disruption and Manganese-enhanced MRI

High-resolution In Vivo Manual Segmentation Protocol for Human Hippocampal Subfields Using 3T Magnetic Resonance Imaging

Simultaneous ex vivo Functional Testing of Two Retinas by in vivo Electroretinogram System

Visual Evoked Potential Recording in a Rat Model of Experimental Optic Nerve Demyelination

High-resolution Structural Magnetic Resonance Imaging of the Human Subcortex In Vivo and Postmortem

In Vivo Gene Transfer to Schwann Cells in the Rodent Sciatic Nerve by Electroporation

In Vivo Fiber-Coupled Pre-Clinical Confocal Laser-scanning Endomicroscopy (pCLE) of Hippocampal Capillaries in Awake Mice

In Vivo Two-photon Imaging of Cortical Neurons in Neonatal Mice

Read Article