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阵列比较基因组杂交（CGH阵列），用于检测基因拷贝数变异的
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JoVE Journal Biologia
Array Comparative Genomic Hybridization (Array CGH) for Detection of Genomic Copy Number Variants
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阵列比较基因组杂交（CGH阵列），用于检测基因拷贝数变异的

DOI:
10.3791/51718-v

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09:16 min

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February 21, 2015

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, , ,
1Cytogenetics Department,Guy’s & St Thomas’ NHS Foundation Trust, 2Cytogenetics Department,Viapath Analytics

Capitoli

  • 00:05Titolo
  • 01:13Labeling Reaction and Purification of DNA
  • 03:47Hybridization
  • 06:30Washing and Scanning Slides
  • 08:50Conclusion

Summary

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阵列CGH为基因拷贝数变异的检测已经取代G-带状核型分析。本文介绍了技术及其在诊断服务实验室的应用。

Tags

Array CGHGenomic Copy Number VariantsDNA LabelingFluorochromesHybridizationOligonucleotide ProbesProbe DensityClinical Diagnostic ServiceGenome AnalysisCopy Number Detection

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