A Novel<em> In vivo</em> Técnica Gene Transferência e<em> In vitro</em> Ensaios baseados em células para o Estudo da perda óssea em Distúrbios Osteomusculares
Differentiation of precursor cells into osteoclasts is regulated by cytokines and growth factors. Here, a novel gene transfer technique for differentiation of osteoclasts in vivo and cell culture protocols for differentiating precursor cells into osteoclasts in vitro as a method to study the effects of cytokines on osteoclastogenesis are described.