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A Novel Model of Mild Traumatic Brain Injury for Juvenile Rats
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Medicina
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JoVE Journal Medicina
A Novel Model of Mild Traumatic Brain Injury for Juvenile Rats

A Novel Model of Mild Traumatic Brain Injury for Juvenile Rats

DOI:
10.3791/51820-v

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07:36 min

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December 08, 2014

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, , , , ,
1Alberta Children’s Hospital Research Institute,University of Calgary, 2Department of Psychiatry and Behavioral Neurosciences,Wayne State University School of Medicine & John D. Dingell VA Medical Center

Capitoli

  • 00:05Titolo
  • 01:22Mild Traumatic Brain Injury (mTBI) Apparatus
  • 02:44Induction of mTBI
  • 03:44Sham Injury
  • 04:22Beam Walking Test
  • 06:13Results: Mild Traumatic Brain Injury
  • 06:58Conclusion

Summary

Traduzione automatica

Traduzione automatica

The modified weight-drop technique is an easy, cost-effective procedure used for the induction of mild traumatic brain injury in juvenile rats. This novel technique produces clinically relevant symptomology that will advance the study of mild traumatic brain injury (mTBI) and concussion.

Tags

Keywords: Mild Traumatic Brain InjuryMTBIJuvenile RatsWeight-drop TechniqueAccelerationDecelerationRotational ForcesPost-concussion SymptomologyRepetitive Brain InjuryBiomechanicsPathophysiology

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