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A Radio-telemetric System to Monitor Cardiovascular Function in Rats with Spinal Cord Transection and Embryonic Neural Stem Cell Grafts
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JoVE Journal Medicina
A Radio-telemetric System to Monitor Cardiovascular Function in Rats with Spinal Cord Transection and Embryonic Neural Stem Cell Grafts

A Radio-telemetric System to Monitor Cardiovascular Function in Rats with Spinal Cord Transection and Embryonic Neural Stem Cell Grafts

DOI:
10.3791/51914-v

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07:59 min

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October 07, 2014

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, ,
1Spinal Cord Research Center, Department of Neurobiology & Anatomy,Drexel University College of Medicine, 2Spinal Cord Injury Center,Heidelberg University Hospital, 3Veterans Administration Medical Center, San Diego, CA, 4Department of Neurosciences,University of California, San Diego

Capitoli

  • 00:05Titolo
  • 01:22Implanting a Radio-telemeter Catheter
  • 03:58Recording the Basal Mean Arterial Pressure and Heart Rate
  • 04:39Colorectal Distension-induced Autonomic Dysreflexia
  • 06:00Results: Physiological and Histological Analyses 8 – 10 weeks Post-graft
  • 07:34Conclusion

Summary

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We present a protocol for using a radio-telemetric system to record cardiovascular parameters in T4 spinal cord transected rats eight weeks after embryonic brainstem neural stem cell grafting into the lesion site. Telemetry is an advanced technique to accurately evaluate cardiovascular function in conscious freely moving spinal cord injured rats.

Tags

Radio-telemetryCardiovascular FunctionSpinal Cord InjuryNeural Stem Cell GraftsBlood PressureHeart RateAutonomic DysreflexiaFemoral Artery Implantation

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