È necessario avere un abbonamento a JoVE per visualizzare questo. Accedi o inizia la tua prova gratuita.
1Department of Pathology,Memorial Sloan Kettering Cancer Center, 2Molecular Pharmacology and Chemistry Program,Memorial Sloan Kettering Cancer Center, 3Department of Radiology,Weill Cornell Medical College, 4Department of Medicine,Memorial Sloan Kettering Cancer Center, 5Department of Oncology,Memorial Sloan Kettering Cancer Center, 6Department of Surgery,Memorial Sloan Kettering Cancer Center
Capitoli
- 00:05Titolo
- 02:30Tissue Procurement
- 04:09Preparation of Materials for Sectioning and Vibratome Settings
- 05:19Tissue Sectioning, Treatment, and Analyses
- 06:25Results: Ex Vivo Metastatic Breast Cancer Response to Heat Shock Protein 90 Inhibitor
- 07:56Conclusion
Etablerade cancer cellinjer och xenotransplantat varit stöttepelaren i cancerforskning under de senaste decennierna. Dock tyder nya bevis som terapeutiskt svar i hög grad påverkas av tumörcellsmikromiljö. Därför har vi tagit fram en ex vivo analys av primära tumörprover för drogutvecklingsändamål.
