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信号衰减为强迫症的大鼠模型
JoVE Journal
Comportamento
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JoVE Journal Comportamento
Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
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信号衰减为强迫症的大鼠模型

DOI:
10.3791/52287-v

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09:29 min

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January 09, 2015

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, , ,
1School of Psychological Sciences,Tel-Aviv University, 2Sagol School of Neuroscience,Tel-Aviv University

Capitoli

  • 00:05Titolo
  • 01:50Handling and Food Restriction
  • 02:33Magazine Training
  • 03:56Lever Press Training: Pre-training Stage
  • 05:19Lever Press Training: Lever Press Training on a Discrete Trial Schedule
  • 06:23Signal Attentuation and Regular Extinction
  • 07:03Testing
  • 07:45Results: Alterations in Signal Attentuation after Drug Intervention
  • 08:32Conclusion

Summary

Traduzione automatica

Traduzione automatica

在本文中描述的协议的目的是诱导大鼠强迫样行为的强迫症（OCD）的研究。此行为是由一个衰减指示的杠杆压响应，有效地生产食品的信号沉淀。

Tags

Obsessive-compulsive DisorderOCDSignal AttenuationRat ModelLever-pressingFeedback CueCompulsive-like BehaviorExtinctionValidated ModelAnti-compulsive EffectsPro-compulsive EffectsNeural Substrate

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