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Modello murino di dall'arteria femorale Wire Injury con impianto di una Perivascolare Drug Delivery Patch
JoVE Journal
Medicina
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JoVE Journal Medicina
Murine Model of Femoral Artery Wire Injury with Implantation of a Perivascular Drug Delivery Patch
DOI:

07:05 min

February 10, 2015

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Capitoli

  • 00:05Titolo
  • 01:24Femoral Artery Isolation
  • 03:00Femoral Artery Wire Injury, Arterial Closure, and Perivascular Drug Patch Implantation
  • 05:53Results: Representative Histological Results at 14 days Post Wire Injury
  • 06:26Conclusion

Summary

Traduzione automatica

We describe a surgical technique that produces wire injury in the femoral artery of mice to induce neointimal hyperplasia to serve as a model testing system for the perivascular delivery of therapeutic compounds for the inhibition of restenosis.

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