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<em> 체외</em> 골수에서 에스트로겐에 민감한 유방암의 휴면 모델 : 분자 메커니즘 연구 및 가설 생성을위한 도구
JoVE Journal
Medicina
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JoVE Journal Medicina
An In Vitro Dormancy Model of Estrogen-sensitive Breast Cancer in the Bone Marrow: A Tool for Molecular Mechanism Studies and Hypothesis Generation
DOI:

08:48 min

June 30, 2015

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Capitoli

  • 00:05Titolo
  • 01:36Clonogenic Assay Plate Preparation
  • 04:13Clonogenic Assay
  • 06:34Results: Pi3 Kinase Inhibitors Activate the Doormant Phenotype in Estrogen Sensitive Cells
  • 07:59Conclusion

Summary

Traduzione automatica

We developed an in vitro model of dormancy in the bone marrow for estrogen-sensitive breast cancer cells. The goal of this protocol is to demonstrate use of the model for the study of the molecular and cellular biology of dormancy and for generation of hypotheses for subsequent testing in vivo.

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