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Surgical Models of Gastroesophageal Reflux with Mice
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Surgical Models of Gastroesophageal Reflux with Mice

Surgical Models of Gastroesophageal Reflux with Mice

DOI:
10.3791/53012-v

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05:19 min

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August 25, 2015

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, ,
1Department of Thoracic Surgery,Ningxia Medical University General Hospital, 2Cancer Research Program,North Carolina Central University, 3Department of Thoracic & Cardiovascular Surgery,The First Affiliated Hospital of Chongqing Medical University, 4Department of Medicine, Center for Esophageal Disease and Swallowing, Division of Gastroenterology and Hepatology,University of North Carolina at Chapel Hill

Capitoli

  • 00:05Titolo
  • 00:49Gastric Reflux Model
  • 02:37Mixed Reflux Model
  • 03:36Duodenal Reflux Model
  • 04:21Results: Representative Mouse Esophageal Epithelium with and without Reflux
  • 04:47Conclusion

Summary

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This article demonstrates surgical procedures of gastroesophageal reflux with mice. These models are useful tools for research on mechanisms and treatment of gastroesophageal reflux disease and potentially Barrett’s esophagus and esophageal adenocarcinoma.

Tags

Keywords: Gastroesophageal RefluxSurgical ModelsMiceReflux EsophagitisEsophagusBarrett’s EsophagusAdenocarcinomaSurgical Procedures

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