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固体脂质纳米粒（前哨淋巴结）细胞内定位的应用

JoVE Journal
Bioingegneria

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JoVE Journal Bioingegneria

Solid Lipid Nanoparticles (SLNs) for Intracellular Targeting Applications

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固体脂质纳米粒（前哨淋巴结）细胞内定位的应用

DOI:

10.3791/53102-v

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08:19 min

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November 17, 2015

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Xiomara Calderón-Colón, Giorgio Raimondi, Jason J. Benkoski, Julia B. Patrone

¹Research and Exploratory Development Department,The Johns Hopkins Applied Physics Laboratory, ²Department of Plastic and Reconstructive Surgery,Johns Hopkins School of Medicine, ³Asymmetric Operations Sector,The Johns Hopkins Applied Physics Laboratory

Capitoli

00:05Titolo
01:41Processing of SLNs
04:10SLNs Interaction with Fibroblasts
06:26Results: SLN Characterization and Interaction with Cellular Models
07:50Conclusion

Summary

Traduzione automatica

In this study, a method for synthesizing ultra-small populations of biocompatible nanoparticles was described, as well as several in vitro methods by which to assess their cellular interactions.

Tags

Keywords: Solid Lipid Nanoparticles (SLNs)Intracellular Targeting Nanoparticle Delivery Fluorescent Dye Phase Inversion Temperature (PIT) Method Biocompatible Nanoparticles MTT Assay Human Dermal Fibroblasts Mouse Dendritic Cells Particle Uptake Fluorescence Microscopy Flow Cytometry

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