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1Wolfson Centre for Age-Related Diseases,King’s College London, University of London, 2Department of Neuroimaging, James Black Centre, Institute of Psychiatry,King’s College London, University of London, 3Institute of Neuroscience and Psychology, Wellcome Surgical Institute, College of Medical, Veterinary and Life Sciences,University of Glasgow, Glasgow, 4Research Service,Edward Hines Jr. VA Hospital, 5Neurology Service,Edward Hines Jr. VA Hospital, 6Department of Molecular Pharmacology and Therapeutics, Neuroscience Research Institute,Loyola University Chicago, 7Department of Oncology, The Gray Institute for Radiation, Oncology and Biology,University of Oxford
Capitoli
- 00:05Titolo
- 01:03Stroke Surgery
- 06:48Confirmation of Infarct and Sample Size Calculation
- 07:39Results: Representative Micro and Macroanatomical Effects of MCA Occlusion on Cerebral Function in the Elderly Rat
- 08:32Conclusion
Här presenterar vi ett protokoll för att producera permanent distala mitten cerebral artärocklusion hos äldre honråttor med samtidig ocklusion av halspulsåder för att generera stora kortikala infarkter och ihållande underskott. Vi visar bekräftelse av skadestorleken med hjälp av strukturell MRI vid 24 timmar och 8 veckor efter stroke.
