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Zeer Stereoselectieve Synthese van 1,6-ketoesters gemedieerd door ionische vloeistoffen: Een drie-componenten reactie Enabling snelle toegang tot een nieuwe klasse met een laag molecuulgewicht Gelators
JoVE Journal
Chimica
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JoVE Journal Chimica
Highly Stereoselective Synthesis of 1,6-Ketoesters Mediated by Ionic Liquids: A Three-component Reaction Enabling Rapid Access to a New Class of Low Molecular Weight Gelators
DOI:

06:31 min

November 27, 2015

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Capitoli

  • 00:05Titolo
  • 01:14Gram-scale Synthesis of Methyl 6-oxo-3,4,6-triphenylhexanoate
  • 03:34Recycling of EMIMAc and Gelation
  • 04:36Results: Analysis of Three-component Synthesis of 1,6-Ketoester
  • 05:35Conclusion

Summary

Traduzione automatica

Ionic liquids (ILs) mediate fast, simple and cheap access to 1,6-ketoesters in high diastereoselectivities and good yields. The reaction protocol is robust and the 1,6-ketoesters can be obtained in gram scale after a simple filtration protocol. Moreover, the 1,6-ketoesters are potent gelators in hydrocarbon solvents.

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