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A Novel Mikro modell för Heterotopisk, En Bloc Chest Wall, Thymus och hjärttransplantation i möss

JoVE Journal
Medicina

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JoVE Journal Medicina

A Novel Microsurgical Model for Heterotopic, En Bloc Chest Wall, Thymus, and Heart Transplantation in Mice

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A Novel Mikro modell för Heterotopisk, En Bloc Chest Wall, Thymus och hjärttransplantation i möss

DOI:

10.3791/53442-v

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12:24 min

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January 23, 2016

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Byoungchol Oh*¹, Georg J. Furtmüller*¹, Michael Sosin*¹, Madeline L. Fryer, Lawrence J. Gottlieb³, Michael R. Christy, Gerald Brandacher^5,6, Amir H. Dorafshar^5,6

¹Johns Hopkins University School of Medicine, ²Burn and Complex Wound Center, ³Section of Plastic and Reconstructive Surgery,University of Chicago Medical Center, ⁴Division of Plastic, Reconstructive, and Maxillofacial Surgery,R Adams Cowley Shock Trauma Center, ⁵Department of Plastic and Reconstructive Surgery,Johns Hopkins University School of Medicine, ⁶Vascularized Composite Allotransplantation (VCA) Lab,Johns Hopkins University School of Medicine

Capitoli

00:05Titolo
01:25Donor Allograft Recovery
06:24Recipient Preparation
08:39Allograft Insert
10:22Results: Heterotropic En Bloc Chest Wall, Thymus and Heart Transplantation
11:19Conclusion

Summary

Traduzione automatica

To study combined solid organ and vascularized composite allotransplantation, we describe a novel heterotopic en bloc chest wall, thymus, and heart transplant model in mice using a cervical non-suture cuff technique.

Tags

Keywords: Heterotopic Chest Wall Transplantation Vascularized Composite Allotransplantation Murine Model Solid Organ Transplantation Vascularized Bone Marrow Thymus Transplantation Heart Transplantation Immunological Research Reconstructive Transplantation Tolerance Induction

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