Rivista
/
Immunologia e infezioni
/
Induktion af Maternal immun aktivering i mus ved Mid-drægtighed Stage med Viral Mimic Poly (I: C)
JoVE Journal
Immunologia e infezioni
È necessario avere un abbonamento a JoVE per visualizzare questo.  Accedi o inizia la tua prova gratuita.
JoVE Journal Immunologia e infezioni
Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic Poly(I:C)

Induktion af Maternal immun aktivering i mus ved Mid-drægtighed Stage med Viral Mimic Poly (I: C)

DOI:
10.3791/53643-v

•

07:13 min

•

March 25, 2016

•

, ,
1Division of Biology and Biological Engineering,California Institute of Technology, 2Harvard Medical School

Capitoli

  • 00:05Titolo
  • 00:57Timed-mating Pair Setup
  • 02:23Poly(I:C) Injection
  • 03:55MIA Adult Offsrping Behavioral Abnormality Evaluation
  • 05:33Results: MIA Adult Offsrping Exhibit Abnormalities Associated with Autism and Schizophrenia
  • 06:42Conclusion

Summary

Traduzione automatica

Traduzione automatica

Maternal immune activation (MIA) is a model for an environmental risk factor of autism and schizophrenia. The goal of this article is to provide a step-by-step procedure of how to induce MIA in the pregnant mice in order to enhance the reproducibility of this model.

Tags

Maternal Immune ActivationMIAMiceViral Mimic Poly(I:C)Mid-gestation StageNeuro-immunologyBrain DevelopmentComportamentoEnvironmental Risk FactorAutismSchizophreniaInduction MethodTimed Mating PairEstrous Cycle SynchronizationEar Punch LabelingDark CycleBody Weight RecordingMale Mouse AdditionPlug Detection

Article

Embed

AGGIUNGI ALLA PLAYLIST

Usage Statistics

Video correlati

check_url/it/53643?article_type=v

Induction of Experimental Autoimmune Hypophysitis in SJL Mice
check_url/it/53643?article_type=v

Seven Steps to Stellate Cells
check_url/it/53643?article_type=v

Measuring Bacterial Load and Immune Responses in Mice Infected with Listeria monocytogenes
check_url/it/53643?article_type=v

Højre ventrikels systoliske tryk Målinger i kombination med Harvest of Lung og Immune vævsprøver i mus
check_url/it/53643?article_type=v

Dissekere medfødte immunforsvar signalering i Viral Evasion af cytokinproduktion
check_url/it/53643?article_type=v

Induktion af murine tarmbetændelse ved adoptiv overførsel af effektor CD4<sup> +</sup> CD45RB<sup> Høj</sup> T celler i immunsvækkede mus
check_url/it/53643?article_type=v

Isolering af leukocytter fra det murine væv på maternel-føtal grænseflade
check_url/it/53643?article_type=v

Induktion af Experimental Autoimmune Encephalomyelitis i mus og evaluering af sygdommen-afhængige Fordeling af immunceller i forskellige væv
check_url/it/53643?article_type=v

Humane placenta og decidua Organ kulturer til at studere Infektioner på Maternal-føtal interface
check_url/it/53643?article_type=v

Bestemmelse immunsystemsuppression versus CNS Beskyttelse for farmakologisk intervention i Autoimmune Demyelinisering

Read Article