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Ein Druckinjektionssystem zur Untersuchung der Neuropharmakologie der Informationsverarbeitung in Awake Behaving Makaken Cortex
JoVE Journal
Comportamento
This content is Free Access.
JoVE Journal Comportamento
A Pressure Injection System for Investigating the Neuropharmacology of Information Processing in Awake Behaving Macaque Monkey Cortex
DOI:

09:46 min

March 14, 2016

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Capitoli

  • 00:05Titolo
  • 00:45Overview of the Injection Process
  • 01:39Preparing the Injection/Recording System
  • 02:49Daily Preparation of the Injection/Recording System
  • 05:20Acute Recordings
  • 07:03Pharmacological Manipulation While Recording
  • 08:17Results: Effect of Scopolamine and Saline on Firing Rate
  • 09:11Conclusion

Summary

Traduzione automatica

Here, we show the pressure injection of neuropharmacological substances during single-cell recording in an awake, behaving macaque monkey. This procedure allows pharmacological manipulation in the direct vicinity of a cortical recording site.

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