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Retroductal Submandibular Gland Instillation and Localized Fractionated Irradiation in a Rat Model of Salivary Hypofunction
JoVE Journal
Medicina
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JoVE Journal Medicina
Retroductal Submandibular Gland Instillation and Localized Fractionated Irradiation in a Rat Model of Salivary Hypofunction
DOI:

07:44 min

April 24, 2016

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Capitoli

  • 00:05Titolo
  • 00:52Submandibular Salivary Gland Cannulation
  • 03:32Submandibular Gland Instillation
  • 04:40Submandibular Gland Localized Fractionated Irradiation
  • 05:35Results: Representative Effect of Fractionated Radiation on Submandibular Gland Function
  • 06:34Conclusion

Summary

Traduzione automatica

Salivary gland hypofunction, a major adverse effect of head and neck radiotherapy diminishes a patient's quality of life. The demonstration of efficacy of new therapies in animal models is a prerequisite before clinical transition. This protocol describes retroductal administration and local irradiation of rat submandibular glands.

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