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微流体流钱伯斯再造使用血止血建模和血小板输注<em>体外</em

JoVE Journal
Bioingegneria

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JoVE Journal Bioingegneria

Microfluidic Flow Chambers Using Reconstituted Blood to Model Hemostasis and Platelet Transfusion In Vitro

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微流体流钱伯斯再造使用血止血建模和血小板输注<em>体外</em

DOI:

10.3791/53823-v

•

10:25 min

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March 19, 2016

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Britt Van Aelst, Hendrik B. Feys, Rosalie Devloo, Philippe Vandekerckhove^3,4, Veerle Compernolle^2,4

¹Transfusion Research Center,Belgium Red Cross-Flanders, ²Blood Service,Belgium Red Cross-Flanders, ³Department of Public Health and Primary Care,Catholic University of Leuven, ⁴Faculty of Medicine and Health Sciences,University of Ghent

Capitoli

00:05Titolo
01:11Flow Chamber Preparation
03:23Preparing the Blood Samples
05:21Perfusion Assay
06:36Data Analysis
07:52Results: Consistency and Utility of the Assay
09:13Conclusion

Summary

Traduzione automatica

Platelet transfusion and hemostasis was modeled using blood reconstitution and microfluidic flow chambers to investigate the function of blood banking platelets. The data demonstrate the consequences of platelet storage lesion on hemostasis, in vitro.

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