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TAPE: A Biodegradable Hemostatic Glue Inspired by a Ubiquitous Compound in Plants for Surgical Application
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JoVE Journal Bioingegneria
TAPE: A Biodegradable Hemostatic Glue Inspired by a Ubiquitous Compound in Plants for Surgical Application

TAPE: A Biodegradable Hemostatic Glue Inspired by a Ubiquitous Compound in Plants for Surgical Application

DOI:
10.3791/53930-v

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08:40 min

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June 08, 2016

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, ,
1The Graduate School of Nanoscience and Technology,Korea Advanced Institute of Science and Technology (KAIST), 2Department of Chemistry,Korea Advanced Institute of Science and Technology (KAIST), 3Center for Systems Biology,Massachusetts General Hospital/Harvard Medical School

Capitoli

  • 00:05Titolo
  • 00:44TAPE Formation
  • 02:09Measuring Adhesive Strength
  • 03:46In Vitro Degradation Test
  • 04:54Hemostatic Ability of TAPE
  • 06:05Results: TAPE Strength, Durability and In Vivo Test Results
  • 07:34Conclusion

Summary

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We describe the simplest protocol to prepare biodegradable medical glue that has an effective hemostatic ability. TAPE is a water-immiscible supramolecular aggregate prepared by mixing of tannic acid, a ubiquitous compound found in plants, and poly(ethylene) glycol, yielding a 2.5 times greater water-resistant adhesion compared with commercial fibrin glue.

Tags

TAPEBiodegradable Hemostatic GlueSurgical ApplicationTannic AcidPEGAdhesive StrengthSealantPorcine Biopsy SkinCyanoacrylate GlueForce-distance CurveWater Resistance

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