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En ortotopiske Mouse Model of Spontan Breast Cancer Metastase
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JoVE Journal Medicina
An Orthotopic Mouse Model of Spontaneous Breast Cancer Metastasis

En ortotopiske Mouse Model of Spontan Breast Cancer Metastase

DOI:
10.3791/54040-v

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08:11 min

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August 14, 2016

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,
1Department of Biochemistry and Molecular Biology, Medical College of Georgia,Augusta University, 2Georgia Cancer Center,Augusta University, 3Charlie Norwood VA Medical Center

Capitoli

  • 00:05Titolo
  • 00:48Orthotopic Breast Cancer Tumor Establishment
  • 02:17Live Mouse Bioluminescent Tumor Growth Imaging
  • 03:24Surgical Primary Tumor Removal
  • 04:36Lung Metastases Validation
  • 06:13Results: Representative Evaluation of Spontaneous Breast Cancer Metastasis
  • 07:00Conclusion

Summary

Traduzione automatica

Traduzione automatica

En ortotopisk brystkreft primær tumor modell og kirurgisk fjerning av primærtumoren for å forlenge liv mus for å generere spontan metastase, er beskrevet. Den tumorvekst og progresjon overvåkes og kvantifiseres ved luciferase fluorescens-avbildning.

Tags

Keywords: Orthotopic Mouse ModelSpontaneous Breast Cancer Metastasis4T1 Luciferase CellsBALB/c MiceBioluminescence ImagingPrimary Tumor GrowthMetastasis Kinetics

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