È necessario avere un abbonamento a JoVE per visualizzare questo. Accedi o inizia la tua prova gratuita.
Capitoli
- 00:05Titolo
- 01:02Dimethylnitrosamine (DMN) Treatment
- 02:15Gross Examination of the Liver
- 03:48Processing, Embedding, and Sectioning of the Liver
- 05:52Masson Trichrome Staining
- 07:01Results: DMN Treated Animals
- 08:20Conclusion
We describe a method to produce an animal model of liver fibrosis in the rat, and assess the degree of fibrosis by histological examination of the liver. The model can be used to study the development of liver disease as well as to test the efficacy of potential anti-fibrotic agents.
