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Modelo Animal avançado de Colorectal metástase no fígado: técnicas de imagem e Propriedades de metastáticos Clones
JoVE Journal
Ricerca sul cancro
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JoVE Journal Ricerca sul cancro
Advanced Animal Model of Colorectal Metastasis in Liver: Imaging Techniques and Properties of Metastatic Clones
DOI:

11:43 min

November 30, 2016

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Capitoli

  • 00:05Titolo
  • 01:14Calibration of Fluorescent Signal Intensity as a Function of Cell Number
  • 02:29Animal Model of Liver Metastases
  • 05:44In Vivo Bioluminescent Imaging
  • 07:58Ex Vivo Fluorescent Imaging
  • 09:05Results: Metastases and Differential Liver Colonization of Colorectal Cancer Cells
  • 10:34Conclusion

Summary

Traduzione automatica

The ability of metastatic clones to colonize distant sites depends on their proliferation capacity and/or their ability to survive in the host microenvironment without significant proliferation. Here, we present an animal model that allows quantitative visualization of both types of liver colonization by metastatic clones.

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