È necessario avere un abbonamento a JoVE per visualizzare questo. Accedi o inizia la tua prova gratuita.
Capitoli
- 00:05Titolo
- 00:44Preparation of Silk Nanoparticles from Bombyx mori Cocoons
- 04:12Preparation of Doxorubicin-loaded Silk Nanoparticles
- 05:28In Vitro Cytotoxicity of Control and Doxorubicin-loaded Silk Nanoparticles
- 06:26Results: Characterization and In Vitro Cytotoxicity of Silk Nanoparticles and Doxorubicin-loaded Silk Nanoparticles
- 08:06Conclusion
Nanoparticles are emerging as promising drug delivery systems for a broad range of indications. Here, we describe a simple yet powerful method to manufacture silk nanoparticles using reverse engineered Bombyx mori silk. These silk nanoparticles can be readily loaded with a therapeutic payload and subsequently explored for drug delivery applications.
