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直接节段性肝内交付使用大鼠肝门部夹具模型方法

JoVE Journal
Medicina

This content is Free Access.

JoVE Journal Medicina

Method of Direct Segmental Intra-hepatic Delivery Using a Rat Liver Hilar Clamp Model

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直接节段性肝内交付使用大鼠肝门部夹具模型方法

DOI:

10.3791/54729-v

•

09:22 min

•

April 02, 2017

•

Eliza W. Beal, Curtis Dumond, Jung-Lye Kim, Khalid Mumtaz, Don Hayes Jr., Ken Washburn, Bryan A. Whitson, Sylvester M. Black

¹Collaboration for Organ Perfusion, Protection, Engineering and Regeneration (COPPER) Lab, Division of Transplant, Department of Surgery, Comprehensive Transplant Center,The Ohio State University Wexner Medical Center

Capitoli

00:05Titolo
00:57Rat Hilar Clamp Placement
05:44Monitoring, Reperfusion and Continued Sampling
07:19Results: Direct Segmental Intrahepatic Delivery of PEG-SOD Using the Rat Hilar Clamp Model
08:43Conclusion

Summary

Traduzione automatica

独特的大鼠肝门部钳模型，为研究药物分子在改善缺血再灌注损伤的影响发展。该模型包括通过门静脉的一个分支门供应到缺血性肝段直接插管，从而允许直接肝递送。

Tags

Keywords: Rat Liver Hilar Clamp Model Ischemia Reperfusion Injury Organ Transplantation Portal Vein Direct Segmental Intrahepatic Delivery Organ Perfusates Liver Transplantation Pharmacologic Molecules Surgical Technique

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