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纵<em>在体内</em>的Cerebrovasculature影像：相关性疾病CNS
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Medicina
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JoVE Journal Medicina
Longitudinal In Vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases
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纵<em>在体内</em>的Cerebrovasculature影像：相关性疾病CNS

DOI:
10.3791/54796-v

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07:47 min

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December 06, 2016

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, , , ,
1Inserm, U1191,Institute of Functional Genomics, 2CNRS,UMR-5203, 3Université de Montpellier

Capitoli

  • 00:05Titolo
  • 01:04Pre-operative Preparation
  • 01:58Vasculature Labeling and Thinned Skull Window Preparation
  • 04:41Two-photon Microscopy
  • 06:12Results: Logitudinal In Vivo Imaging of the Cerebrovasculature
  • 07:10Conclusion

Summary

Traduzione automatica

Traduzione automatica

该原稿描述的过程使用纵向双光子显微镜体内淀粉样蛋白斑积累期间跟踪cerebrovasculature的重塑。减薄头骨制备使荧光染料的可视化，以评估在阿尔茨海默氏病的小鼠模型中脑血管损伤的进展。

Tags

Keywords: In Vivo ImagingCerebrovasculatureCNS DiseasesNeuroscienzeVascular RemodelingMinimally InvasivePial VesselsPenetrating Cortical VesselsBlood-brain BarrierFITC-dextranRetro-orbital InjectionHead Mount DeviceCyanoacrylic Glue

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