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Bevestiging van de Myocardiale ischemie en reperfusie schade in Muizen met behulp van Surface Pad elektrocardiografie
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JoVE Journal Medicina
Confirmation of Myocardial Ischemia and Reperfusion Injury in Mice Using Surface Pad Electrocardiography
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Bevestiging van de Myocardiale ischemie en reperfusie schade in Muizen met behulp van Surface Pad elektrocardiografie

DOI:
10.3791/54814-v

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09:23 min

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November 24, 2016

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,
1Department of Biomedical Sciences, James H. Quillen College of Medicine,East Tennessee State University, 2James H. Quillen Veterans Affairs Medical Center

Capitoli

  • 00:05Titolo
  • 00:39Electrocardiogram (ECG) Acquisition
  • 01:46Surgical Procedure and ECG Recording
  • 05:46ECG Reperfusion Confirmation
  • 07:02Results: Typical ECG Changes Over the Course of an Ischemia/Reperfusion Surgery
  • 08:42Conclusion

Summary

Traduzione automatica

Traduzione automatica

During murine myocardial ischemia/reperfusion surgery, correct placement of the occluding ligature is typically confirmed by visible observation of myocardial pallor. Herein, a method of electrocardiographically confirming ischemia and reperfusion, to supplement observed myocardial pallor, is demonstrated in male C57Bl/6 mice.

Tags

ElectrocardiographyMyocardial IschemiaReperfusion InjuryMiceECG PadElectrolyte GelAnesthetizedR WaveQ WaveIschemia ReperfusionSurgical SiteTracheaVentilation TubingRodent Ventilator

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