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临床前小鼠模型的外科手术和方法<em> De Novo</em>乳腺癌转移
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Surgical Procedures and Methodology for a Preclinical Murine Model of De Novo Mammary Cancer Metastasis
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临床前小鼠模型的外科手术和方法<em> De Novo</em>乳腺癌转移

DOI:
10.3791/54852-v

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08:41 min

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July 29, 2017

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, , ,
1Cell, Developmental & Cancer Biology,Oregon Health & Science University, 2University of Minnesota, 3Knight Cancer Institute,Oregon Health & Science University

Capitoli

  • 00:00Titolo
  • 00:30Introduction
  • 01:20Sterilization of Surgical Site
  • 02:06Primary Tumor Exposure
  • 03:15Removal of Primary Tumor
  • 06:06Wound Closure
  • 07:35Representative Results
  • 07:55Conclusion

Summary

Traduzione automatica

Traduzione automatica

评估靶向乳腺癌转移的辅助治疗的临床前模型缺乏。为了解决这个问题，我们开发了从头肺乳腺癌转移，其特征在于，在辅助设定（后手术切除原发肿瘤的）给药的治疗可以为疗效影响先前接种的肺转移进行评估的鼠模型。

Tags

Murine ModelMammary CancerMetastasisPreclinicalSurgical ResectionMMTV-PyMTOrthotopic InjectionPrimary TumorLung Metastasis

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