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En mikrofluidsystem med Surface mønster for Undersøgelse Kavitation Bubble (r)-Cell Interaktion og de resulterende bioeffekter på Single-celle niveau
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Capitoli
- 00:05Titolo
- 00:49Gold Dot Patterning
- 04:19Fabricating the Molecular-assembly Patterning by Lift-off (MAPL)
- 06:17Chip Assembly and Bubble Investigation
- 09:11Results: Shear Stress and Membrane Dynamics of Single Cells from Bubble Interactions
- 10:46Conclusion
A microfluidic chip was fabricated to produce pairs of gold dots for tandem bubble generation and fibronectin-coated islands for single-cell patterning nearby. The resultant flow field was characterized by particle image velocimetry and was employed to study various bioeffects, including cell membrane poration, membrane deformation, and intracellular calcium response.
