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En omfattende prosedyre for å evaluere<em> I Vivo</em> Utførelse av kreft Nanomedicines
JoVE Journal
Ricerca sul cancro
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JoVE Journal Ricerca sul cancro
A Comprehensive Procedure to Evaluate the In Vivo Performance of Cancer Nanomedicines
DOI:

07:59 min

March 04, 2017

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Capitoli

  • 00:05Titolo
  • 00:56Synthesis of Dual-labeled Liposomal Nanoparticles
  • 03:22In Vivo PET-CT Imaging and Ex Vivo Biodistribution Measurements
  • 06:19Results: Biodistribution of Fluorescent- and Radiolabeled Nanoparticles in Tumor-bearing Mice
  • 07:14Conclusion

Summary

Traduzione automatica

The poor understanding of the in vivo performance of nanomedicines stymies their clinical translation. Procedures to evaluate the in vivo behavior of cancer nanomedicines at systemic, tissue, single-cell, and subcellular levels in tumor-bearing immunocompetent mice are described here. This approach may help researchers to identify promising cancer nanomedicines for clinical translation.

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