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Developmental Biology

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JoVE Journal Developmental Biology
Præcis Cellular Ablation Approach for modellering af akut nyreskade i udviklingen af ​​zebrafisk
 
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Præcis Cellular Ablation Approach for modellering af akut nyreskade i udviklingen af ​​zebrafisk

Article DOI: 10.3791/55606-v • 09:53 min • June 3rd, 2017
June 3rd, 2017 •
1, 1, 2, 1, 1, 1
1Department of Biomedical Sciences, NYITCOM, 2Department of Basic Sciences, NYITCOM-A-State

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Dette arbejde præsenterer en ny in vivo model af segmental nyreskade ved brug af nyre GFP transgene zebrafisk. Modellen tillader induktion af målrettet ablation af nyrepitelceller for at vise de cellulære mekanismer for nephronskader og reparation.

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Udviklingsbiologi udgave 124 nyre zebrafisk GFP epithelcelle laser fotoablation konfokal
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