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Journal / Medicine / Intravital Microscopy of Monocyte Homing and…
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Intravital Microscopy of Monocyte Homing and Tumor-Related Angiogenesis in a Murine Model of Peripheral Arterial Disease
 

Intravital Microscopy of Monocyte Homing and Tumor-Related Angiogenesis in a Murine Model of Peripheral Arterial Disease

Article DOI: 10.3791/56290-v • 08:38 min • August 26th, 2017
August 26th, 2017 •
1, 1, 2, 3, 1, 1, 4, 1, 1
1Department of Cardiology and Angiology, University of Magdeburg, 2Leibniz Institute for Neurobiology, 3Institute of Molecular and Clinical Immunology, University of Magdeburg, 4Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School

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Monocytes are important mediators of arteriogenesis in the context of peripheral arterial disease. Using a basement membrane-like matrix and intravital microscopy, this protocol investigates monocyte homing and tumor-related angiogenesis after monocyte injection in the femoral artery ligation murine model.

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Keywords: Intravital Microscopy Monocyte Homing Tumor-related Angiogenesis Peripheral Arterial Disease Cell Labeling Matrigel VEGF BFGF Heparin Subcutaneous Injection Systemic Cell Application
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