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C57BL/6 小鼠自身免疫性神经炎的功能和病理评价的简易方法
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Neuroscienze
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JoVE Journal Neuroscienze
A Simple Approach to Induce Experimental Autoimmune Neuritis in C57BL/6 Mice for Functional and Neuropathological Assessments
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C57BL/6 小鼠自身免疫性神经炎的功能和病理评价的简易方法

DOI:
10.3791/56455-v

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07:30 min

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November 09, 2017

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, , , , ,
1Department of Anatomy and Neuroscience, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences,The University of Melbourne

Capitoli

  • 00:05Titolo
  • 01:02Experimental Autoimmune Neuritis (EAN) Motor Function Testing and Clinical Scoring
  • 04:11Results: Representative Analysis of P0180-199 Peptide-induced EAN Pathology
  • 05:59Conclusion

Summary

Traduzione automatica

Traduzione automatica

本报告概述了一个简单的方法, 成功诱导实验性自身免疫神经炎 (一) 使用髓磷脂蛋白零 (P0)180-199肽结合弗氏的完整佐剂和百日咳毒素。我们提出了一个复杂的范例, 能够准确地评估在这一过程中出现的功能性赤字和神经病的程度。

Tags

Experimental Autoimmune NeuritisEANMouse ModelPeripheral NeuropathyMotor Function AssessmentPertussis ToxinMycobacterium TuberculosisComplete Freund’s AdjuvantGait Function Imaging SystemClinical Scoring

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