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Trans-tympaniske Drug Delivery til behandling af ototoksicitet
JoVE Journal
Medicina
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JoVE Journal Medicina
Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity
DOI:

09:52 min

March 16, 2018

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Capitoli

  • 00:04Titolo
  • 00:57Auditory Brainstem Response (ABR)
  • 01:59Trans-tympanic Injection
  • 03:55Cochlea Dissection and Decalcification
  • 04:38Cryosectioning and Immunohistochemistry
  • 07:37Results: Representative Effects of Trans-tympanic Drug/Biologic Delivery to the Rat Cochlea
  • 09:20Conclusion

Summary

Traduzione automatica

Vi præsenterer en teknik til lokaliserede administration af narkotika gennem ruten trans-tympaniske ind i cochlea. Medicinafgivelse gennem denne rute ville ikke forstyrre anti-cancer effekt af de kemoterapeutiske stoffer såsom cisplatin.

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