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Subretinal transplantasjon av menneskelige embryonale stamcelleforskningen avledet retinal Pigment epitelceller i store øyne modell av geografiske Atrophy
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Biologia
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JoVE Journal Biologia
Subretinal Transplantation of Human Embryonic Stem Cell Derived-retinal Pigment Epithelial Cells into a Large-eyed Model of Geographic Atrophy

Subretinal transplantasjon av menneskelige embryonale stamcelleforskningen avledet retinal Pigment epitelceller i store øyne modell av geografiske Atrophy

DOI:
10.3791/56702-v

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11:03 min

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January 22, 2018

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, , , , ,
1Clinical Neuroscience, Section for Ophtalmology and Vision,Karolinska Institutet, 2Clinical Sciences, Intervention and Technology, Division of Obstetrics and Gynecology,Karolinska Institutet

Capitoli

  • 00:05Titolo
  • 01:12Subretinal Injection of Sodium Iodate into a Large-eyed Animal Model
  • 04:36Subretinal Transplantation of hESC-RPE Cells in Treated Animals
  • 07:35In Vivo Retinal and Subretinal Imaging
  • 08:47Results: Transplantation of Human Embryonic Stem Cell Derived-retinal Pigment Epithelial Cells
  • 10:22Conclusion

Summary

Traduzione automatica

Traduzione automatica

Netthinnens pigment epitelceller kunne tjene som en erstatning for cellen terapi for avansert form av tørre aldersrelatert makuladegenerasjon. Denne protokollen beskriver generering av en stor-eyed modell av geografiske atrofi og subretinal transplantasjon av menneskelige embryonale Stamcelle-avledet netthinnens pigment epitelceller i denne modellen av sykdom.

Tags

Subretinal TransplantationHuman Embryonic Stem CellRetinal Pigment Epithelial CellsLarge-eyed Animal ModelGeographic AtrophyRegenerative MedicineAge-related Macular DegenerationOptical Coherence TomographyMicrosurgeryPars Plana TechniqueVitrectomySubretinal Injection

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