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Mouse Models Of Helicobacter Infection And Gastric Pathologies
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Immunologia e infezioni
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JoVE Journal Immunologia e infezioni
Mouse Models Of Helicobacter Infection And Gastric Pathologies

Mouse Models Of Helicobacter Infection And Gastric Pathologies

DOI:
10.3791/56985-v

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07:43 min

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October 18, 2018

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, , ,
1Centre for Innate Immunity and Infectious Diseases,Hudson Institute of Medical Research, 2Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology,Monash University

Capitoli

  • 00:04Titolo
  • 01:11Intragastric Helicobacter Gavage
  • 03:25Tissue Harvest
  • 04:39Bacterial Stomach Colonization Confirmation
  • 05:45Results: Helicobacter Detection in Mouse Stomach Tissue Post-intragastric Infection
  • 07:17Conclusion

Summary

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Mice represent an invaluable in vivo model to study infection and diseases caused by gastrointestinal microorganisms. Here, we describe the methods used to study bacterial colonization and histopathological changes in mouse models of Helicobacter pylori-related disease.

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Keywords: Mouse ModelHelicobacter InfectionGastric PathologiesMicrobiotaInflammationCancerPathogenesisGastrointestinal PathogensBacterial InoculumH. PyloriH. FelisMouse ColonizationIn Vitro SubcultureBacterial ViabilityBacterial MotilityGastric InoculationMouse RestraintEsophageal CatheterizationBacterial Dose

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