Waiting
Elaborazione accesso...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Developmental Biology / Three-dimensional Inflammatory Human Tissue…
JoVE Journal
Developmental Biology

È necessario avere un abbonamento a JoVE per visualizzare questo Contenuto. Accedi o inizia la tua prova gratuita.

JoVE Journal Developmental Biology
Three-dimensional Inflammatory Human Tissue Equivalents of Gingiva
 

Three-dimensional Inflammatory Human Tissue Equivalents of Gingiva

Article DOI: 10.3791/57157-v • 08:43 min • April 3rd, 2018
April 3rd, 2018 •
1, 2, 2
1Department of Pharmacology, The Nippon Dental University, 2Department of Oral and Maxillofacial Surgery, The Nippon Dental University Hospital

Capitoli

Riepilogo
Automatic Translation

The goal of the protocol is to build an inflammatory human gingiva model in vitro. This tissue model co-cultivates three types of human cells, HaCaT keratinocytes, gingival fibroblasts, and THP-1 macrophages, under three-dimensional conditions. This model can be applied to investigating periodontal diseases, such as gingivitis and periodontitis.

Tags

Keywords: 3D Inflammatory Gingiva Tissue Model In Vitro Human Cells Wound Healing Tissue Regeneration Inflammation Periodontal Diseases Collagen HGF HaCaT Culture Insert Culture Medium Cell Suspension Co-culture
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter