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A Method for the Measurement of Salivary Gland Function in Mice
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Immunologia e infezioni
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JoVE Journal Immunologia e infezioni
A Method for the Measurement of Salivary Gland Function in Mice

A Method for the Measurement of Salivary Gland Function in Mice

DOI:
10.3791/57203-v

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07:29 min

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January 25, 2018

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, , , , , ,
1Arthritis and Clinical Immunology,Oklahoma Medical Research Foundation

Capitoli

  • 00:05Titolo
  • 00:56Preparations
  • 02:26Saliva Collection
  • 05:17Results: Strain Variation and Induced Salivary Gland Hypofunction
  • 06:38Conclusion

Summary

Traduzione automatica

Traduzione automatica

Salivary gland hypofunction is a frequent consequence of autoimmune disease and radiation therapy. Reproducible evaluation of salivary gland function in mouse models of these diseases is a technical challenge. Here, a simple method for accurate and reproducible measurement of saliva production in mice is described.

Tags

Saliva CollectionSalivary Gland FunctionPilocarpine StimulationMouse ModelSjogren’s SyndromeSalivary Gland FibrosisSalivary Gland RegenerationAbsorbent SwabsKetamineXylazineAnesthesiaRestraintBioactive Molecules

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