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PET-billeddannelse af Neuroinflammation ved hjælp af [11C] DPA-713 i en musemodel af iskæmisk slagtilfælde
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Medicina
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JoVE Journal Medicina
PET Imaging of Neuroinflammation Using [11C]DPA-713 in a Mouse Model of Ischemic Stroke

PET-billeddannelse af Neuroinflammation ved hjælp af [11C] DPA-713 i en musemodel af iskæmisk slagtilfælde

DOI:
10.3791/57243-v

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12:01 min

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June 14, 2018

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, , ,
1Department of Radiology,Stanford University, 2Department of Neurology and Neurological Sciences,Stanford University

Capitoli

  • 00:05Titolo
  • 02:20CT Acquisition
  • 03:34PET Acquistion
  • 05:48Dynamic PET Image Analysis
  • 10:23Results: [11C]DPA-713 is Effective in Quantifying Neuroinflammation in the dMCAO Mouse Model of Stroke
  • 11:00Conclusion

Summary

Traduzione automatica

Traduzione automatica

Positronemissionstomografi (PET) billeddannelse af translocator protein 18 kDa (TSPO) giver en non-invasiv måde at visualisere den dynamiske rolle, neuroinflammation i udvikling og progression af hjernesygdomme. Denne protokol beskriver TSPO-PET og ex vivo Autoradiografi for at registrere neuroinflammation i en musemodel af iskæmisk slagtilfælde.

Tags

Keywords: PET ImagingNeuroinflammation[11C]DPA-713Mouse ModelIschemic StrokeTSPOAutoradiographyBrain DiseasesDynamic ImagingRadiotracer

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