È necessario avere un abbonamento a JoVE per visualizzare questo. Accedi o inizia la tua prova gratuita.
Capitoli
- 00:05Titolo
- 00:44Experimental Preparation
- 01:40Accessing and Visualizing Ductal Entry Point
- 02:39Ductal Cannulation and Line Placement
- 05:04Injection
- 05:52Results: Confirmation of Retroductal Nanoparticle Persistence 24 Hours Post Injection
- 06:50Conclusion
Local drug delivery to the submandibular glands is of interest in understanding salivary gland biology and for the development of novel therapeutics. We present an updated and detailed retroductal injection protocol, designed to improve delivery accuracy and experimental reproducibility. The application presented herein is the delivery of polymeric nanoparticles.
