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Rodent Behavioral Testing to Assess Functional Deficits Caused by Microelectrode Implantation in the Rat Motor Cortex
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Rodent Behavioral Testing to Assess Functional Deficits Caused by Microelectrode Implantation in the Rat Motor Cortex

Rodent Behavioral Testing to Assess Functional Deficits Caused by Microelectrode Implantation in the Rat Motor Cortex

DOI:
10.3791/57829-v

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10:42 min

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August 18, 2018

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, , , , , ,
1Advanced Platform Technology Center, Rehabilitation Research and Development,Louis Stokes Cleveland Department of Veterans Affairs Medical Center, 2Department of Biomedical Engineering,Case Western Reserve University

Capitoli

  • 00:04Titolo
  • 00:31Microelectrode Implantation Surgical Procedure
  • 03:16Insertion of Microelectrode in Motor Cortex
  • 04:57Behavioral Testing
  • 08:16Results: Representative Ladder Test and Grip Strength Test Results
  • 09:57Conclusion

Summary

Traduzione automatica

Traduzione automatica

We have shown that a microelectrode implantation in the motor cortex of rats causes immediate and lasting motor deficits. The methods proposed herein outline a microelectrode implantation surgery and three rodent behavioral tasks to elucidate potential changes in the fine or gross motor function due to implantation-caused damage to the motor cortex.

Tags

Keywords: RodentBehavioral TestingFunctional DeficitsMicroelectrode ImplantationRat Motor CortexNeural EngineeringMotor FunctionSurgical ProcedureStereotaxic FrameCephalosporin AntibioticBupivacaineBetadineCyanoacrylateDental CementDuraMotor CortexForepaw Movement

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