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双正电子发射层析成像用 68 ga 芯掺杂氧化铁纳米粒子的合成/(t1) 磁共振成像
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Biologia
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JoVE Journal Biologia
Synthesis of 68Ga Core-doped Iron Oxide Nanoparticles for Dual Positron Emission Tomography /(T1)Magnetic Resonance Imaging
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双正电子发射层析成像用 68 ga 芯掺杂氧化铁纳米粒子的合成/(t1) 磁共振成像

DOI:
10.3791/58269-v

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07:26 min

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November 20, 2018

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, , ,
1Nanobiotechnology, Molecular Imaging and Metabolomics Lab,Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 2CIC biomaGUNE and CIBER de Enfermedades Respiratorias (CIBERES). Ikerbasque, Basque Foundation for Science,Universidad Complutense de Madrid (UCM), 3Advanced Imaging Unit, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC),CIBER de Enfermedades Respiratorias (CIBERES)

Capitoli

  • 00:04Titolo
  • 00:26Synthesis of Citrate-Coated Iron Oxide Nanoparticles
  • 01:41Synthesis of 68Ga Core-Doped Iron Oxide Nanoparticles (68Ga-C-IONP)
  • 03:19Analysis of 68Ga Core-Doped Iron Oxide Nanoparticles (68Ga-C-IONP)
  • 04:42Results: Characterization of 68Ga Core-Doped Iron Oxide Nanoparticles
  • 06:40Conclusion

Summary

Traduzione automatica

Traduzione automatica

在这里, 我们提出了一个协议,以获得68ga 掺杂氧化铁纳米粒子通过快速微波驱动合成。该方法使 pet/i 1) mri 纳米颗粒在20分钟的合成中具有90% 以上的放射性标记效率和99% 的放射化学纯度。

Tags

Keyword Extraction:68GaCore-dopedIron Oxide NanoparticlesDual PET/MR ImagingMicrowave SynthesisReproducibleIron Chloride HexahydrateCitric Acid Trisodium Salt DihydrateHydrazine HydrateGel Filtration Desalting ColumnGallium-68 GeneratorGallium-68 ChlorideHydrodynamic Size

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