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1Department of Pharmacology and Toxicology,The University of Mississippi Medical Center, 2Department of Medicine, Division of Nephrology,Rush University Medical Center, 3Department of Medicine, Division of Nephrology,The University of Mississippi Medical Center, 4Department of Neurology,The University of Mississippi Medical Center
Chapters
- 00:04Title
- 01:34Kidney Isolation
- 02:33Kidney Homogenization, Incubation, and Straining
- 05:10Glomeruli Enumeration and Nephron Number Extrapolation
- 06:20Results: Representative Nephron Quantification
- 07:11Conclusion
Estimater af hele nyre Neron nummer er vigtige klinisk og eksperimentelt, da der er en omvendt sammenhæng mellem Neron nummer og en øget risiko for renal og hjerte-kar-sygdom. Heri, brugen af syre maceration metode, som giver hurtige og pålidelige estimater af hele nyre Neron nummer, er påvist.
