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Automated Behavioral Analysis of Large C. elegans Populations Using a Wide Field-of-view Tracking Platform
JoVE Journal
Immunologia e infezioni
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JoVE Journal Immunologia e infezioni
Automated Behavioral Analysis of Large C. elegans Populations Using a Wide Field-of-view Tracking Platform

Automated Behavioral Analysis of Large C. elegans Populations Using a Wide Field-of-view Tracking Platform

DOI:
10.3791/58643-v

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07:20 min

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November 28, 2018

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, , , , , ,
1Centre for Misfolding Diseases, Department of Chemistry,University of Cambridge, 2European Research Institute for the Biology of Aging,University Medical Centre Groningen

Capitoli

  • 00:04Titolo
  • 01:05Wide Field-of-View Nematode Tracking Platform (WF-NTP) Procedure
  • 03:40Video Data Analysis
  • 05:52Results: Representative Applications Enabled by the WF-NTP Method
  • 06:31Conclusion

Summary

Traduzione automatica

Traduzione automatica

We describe protocols for using the wide field-of-view nematode tracking platform (WF-NTP), which enables high-throughput phenotypic characterization of large populations of Caenorhabditis elegans. These protocols can be used to characterize subtle behavioral changes in mutant strains or in response to pharmacological treatment in a highly scalable fashion.

Tags

C. ElegansAutomated Behavioral AnalysisDrug DiscoveryMisfolding DiseasesAgingGenetic ScreeningsParallel Worm TrackerImage Capture Software

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