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小鼠 mptp 诱导的帕金森病模型中自发性运动的行为评估
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Behavioral Assessments of Spontaneous Locomotion in a Murine MPTP-induced Parkinson’s Disease Model
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小鼠 mptp 诱导的帕金森病模型中自发性运动的行为评估

DOI:
10.3791/58653-v

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05:38 min

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January 07, 2019

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, , , , , ,
1State Key Laboratory of Medicinal Chemical Biology, The Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Science,Nankai University

Capitoli

  • 00:04Titolo
  • 00:42Cylinder Test
  • 02:44Open Field Test
  • 03:36Results: Performance on the Cylinder and Open Field Tests Following MPTP Administration
  • 04:49Conclusion

Summary

Traduzione automatica

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我们描述了使用 mptp 建立帕金森病小鼠模型, 以及使用圆筒和开放场测试测量运动功能的行为评估。然后, 我们使用 l-dopa 作为一个例子, 说明如何将这个模型应用于 pd 药物的研究。

Tags

Keywords: Behavioral AssessmentSpontaneous LocomotionMPTP-inducedParkinson’s Disease ModelCylinder TestOpen Field TestPaw LiftMotor FunctionL-DOPAVideo RecordingEnvironmental InterferenceAcclimationSanitization

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