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闪速纳米沉淀法包聚物纳米粒子中疏水亲水化合物的作用

JoVE Journal
Bioingegneria

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JoVE Journal Bioingegneria

Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles

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闪速纳米沉淀法包聚物纳米粒子中疏水亲水化合物的作用

DOI:

10.3791/58757-v

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10:12 min

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January 07, 2019

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Chester E. Markwalter*, Robert F. Pagels*, Brian K. Wilson*, Kurt D. Ristroph*, Robert K. Prud’homme*

¹Department of Chemical and Biological Engineering,Princeton University

Capitoli

00:04Titolo
00:51Encapsulation of Hydrophobic Compounds in Polymeric Nanoparticles (NPs) Using a Confined Impinging Jet (CIJ) Mixer
04:08Encapsulation of Ovalbumin in Inverted NPs Using a Small-Scale Multi-Inlet Vortex Mixer (MIVM)
06:44Modifications for Larger-Scale Formulation
07:33Results: Flash NanoPrecipitation (FNP) of Polymeric Nanoparticles with Hydrophobic and Hydrophilic Cores
09:08Conclusion

Summary

Traduzione automatica

闪速纳米降水 (fnp) 是一种可扩展的制备聚合物核壳纳米粒子的方法。描述了用于疏水或亲水性疗法封装的实验室规模配方。

Tags

Keywords: Flash Nanoprecipitation IFNP Inverse Flash Nanoprecipitation Polymeric Nanoparticles Hydrophobic Compounds Hydrophilic Compounds CIJ Mixer Syringe Pumps Anti-solvent Quench Bath Vitamin E Block Copolymer Stabilizer

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