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Journal / Bioengineering / A Tripeptide-Stabilized Nanoemulsion of Oleic Acid
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Bioengineering

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JoVE Journal Bioengineering
A Tripeptide-Stabilized Nanoemulsion of Oleic Acid
 

A Tripeptide-Stabilized Nanoemulsion of Oleic Acid

Article DOI: 10.3791/59034-v • 10:42 min • February 27th, 2019
February 27th, 2019 •
1, 1,2, 1,3, 4,5,6, 1,2,3
1Department of Chemistry, Brooklyn College, The City University of New York, 2Ph.D. Program in Chemistry, The Graduate Center of The City University of New York, 3Ph.D. Program in Biochemistry, The Graduate Center of The City University of New York, 4Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 5Women's Health Research Institute, Icahn School of Medicine at Mount Sinai, 6Laboratory for Translational Research, Western Connecticut Health Network

Capitoli

Riepilogo
Automatic Translation

This protocol describes an efficient method to synthesize a nanoemulsion of an oleic acids-platinum(II) conjugate stabilized with a lysine-tyrosine-phenylalanine (KYF) tripeptide. The nanoemulsion forms under mild synthetic conditions via self-assembly of the KYF and the conjugate.

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Keywords: Tripeptide Nanoemulsion Oleic Acid Cisplatin Platinum Ovarian Cancer Peptide Modification Diagnostic Pharmaceutical In-vivo Studies Fmoc L-phenylalanine L-tyrosine TBTU DIPEA
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