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小鼠脑脊髓子宫转导后超微结构神经可塑性参数的评价

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Biologia dello sviluppo

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JoVE Journal Biologia dello sviluppo

Assessment of Ultrastructural Neuroplasticity Parameters After In Utero Transduction of the Developing Mouse Brain and Spinal Cord

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小鼠脑脊髓子宫转导后超微结构神经可塑性参数的评价

DOI:

10.3791/59084-v

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10:28 min

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February 26, 2019

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David Lutz*¹, Monika von Düring*¹, Franco Corvace, Luzie Augustinowski, Anne-Kathrin Trampe, Marzena Nowak, Eckart Förster

¹Department of Neuroanatomy and Molecular Brain Research,Ruhr University Bochum, ²Central Animal Facility of the Medical Faculty,Ruhr University Bochum

Capitoli

00:04Titolo
01:22In Utero Transduction
03:13Telemacrophotographic Imaging
04:12Transmission Electron Microscopy Tissue Preparation
06:13Ultrastructural Neuroplasticity Parameter Selection
07:44Results: Representative Ultrastructural Imaging of In Utero-Transduced Mouse Embryonic Tissues
09:23Conclusion

Summary

Traduzione automatica

透射电子显微镜和子宫转导的结合是研究神经系统发育过程中精细超微结构形态变化的有力方法。这种组合方法可以深入了解神经可塑性相对于其地形表现的结构细节的变化。

Tags

Keywords: Ultrastructural Neuroplasticity In Utero Transduction Mouse Brain Spinal Cord Congenital Neurodegenerative Diseases Adeno-associated Virus Embryonic Development Electron Microscopy

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